The Notardomenico is a black grape variety native to Puglia, specifically in the area around Brindisi, where it has been present since ancient times, although the cultivated area is quite modest. It is generally grown and vinified in a blend with Ottavianello, another indigenous variety from the Brindisi area, which tends to overshadow it with its more intense aromatic profile. Di Rovasenda, in his 1877 work, mentions this variety but does not provide any ampelographic descriptions. Little is known about the origin of its unusual name. Unlike Sussumaniello and Ottavianello, Notardomenico is rarely vinified as a single-varietal wine, although some producers have experimented with it. The resulting wine is ruby red with violet hues, fairly balanced, and exhibits spicy aromas. Its moderate alcohol content and anthocyanin levels make it suitable for producing rosé wines, either in purity or blended with other varieties.

The Notardomenico grape is sparsely cultivated, with medium to small clusters that are conical or cylindrical, simple or winged, and moderately compact. The berries display a beautiful dark red color with violet hues. In some towns within the Brindisi region, Notardomenico grapes play a significant role in the production of rosé wines.